The primary objective of this study is to characterize the pharmacokinetics (PK) profile of a single dose of AMG 592 administered subcutaneously in healthy Japanese participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
18
Research Site
Randwick, New South Wales, Australia
Maximum Observed Serum Concentration (Cmax) of AMG 592
Time frame: Up to Day 43
Time of Maximum Observed Concentration (tmax) of AMG 592
Time frame: Up to Day 43
Area Under the Serum Concentration-time Curve to the Last Measurable Point (AUClast) of AMG 592
Time frame: Up to Day 43
Area Under the Concentration-time Curve (AUC) from Time Zero to Infinity (AUCinf)
Time frame: Up to Day 43
Number of Participants who Experience Treatment-emergent Adverse Events (TEAEs)
Time frame: Day 1 to Day 43
Number of Participants who Experience Anti-AMG 592 Antibodies Formation
Time frame: Up to Day 43
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