Intensified chemotherapy is an effective treatment in 30-70% of patients with refractory germ cell tumor. Since most cases are diagnosed before the age of 40, survivors can expect to live another 30 to 50 years after being successfully treated. Long-term side effects and physical and emotional consequences can therefore have a significant impact on daily life. To date, no data of this type is available in France. This study will help clinicians better understand the long-term consequences for relapsed patients receiving high-dose chemotherapy.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
180
EORTC-QLQ C-30 questionnaire The Impact of Events Scale (IES-R) Multi-Dimensional Fatigue Inventory The EORTC-QLQ C-30 Vers. 3
Gustave Roussy
Villejuif, France
RECRUITINGCompare the quality of life between the three groups measured with the EORTC-QLQ C-30 questionnaire.
To compare the quality of life in long-term survivors of germ cell cancers after high-dose chemotherapy and autologous stem cell transplant with a group of coetaneous patients treated by orchidectomy only for localized testicular tumor and a group of patients of the same age treated with first line cisplatin-based chemotherapy for good or intermediate prognosis advanced germ cell tumor.
Time frame: Day 1
Compare late side effects between the three groups.
Time frame: Day 1
Compare correlated morbidities between the three groups.
Time frame: Day 1
Compare fatigue measured by the MFI-20 scale between the three groups.
Time frame: Day 1
Compare symptoms of post-traumatic stress measured by the IES scale between the three groups.
Time frame: Day 1
Compare current social and professional situation between the three groups.
Time frame: Day 1
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