To engineer immune organoids from pediatric patient tissues using induced-pluripotent stem cells (iPSC)
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
108
Skin biopsy
Fresh tumor sample
Blood sample in heparin tubes (highly recommended), to be collected before starting treatment or as soon as hematological recovery has been reached
Gustave Roussy
Villejuif, France
RECRUITINGHopital Necker
Paris, Île-de-France Region, France
RECRUITINGProportion of viable and exploitable immune organoids with engrafted tumor cells
Time frame: until 5 years after enrolment
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Healthy tissue from the tumor site whenever possible
Spinal cerebrospinal fluid (SCF) whenever possible