Relationship of Epicardial Adiposity With Sedentary Time, Physical Activity and Performance in Hypertensives

Karamanoğlu Mehmetbey University40 enrolled

Overview

Epicardial adipose tissue is associated with the development of cardiovascular disease and its increase is positively correlated with blood pressure elevation in hypertensive individuals. In the literature, being physically active has been shown to be effective in the treatment of hypertension and reduction of epicardial adipose tissue thickness. The aim of this study was to evaluate the relationship between epicardial adipose tissue thickness and sedentary time, physical activity level and physical performance in patients with hypertension. The study included 40 patients with hypertension. The physical and demographic characteristics of the participants were collected using a sociodemographic form. Waist/hip circumference was measured with tape measure and epicardial adipose tissue thickness with echocardiography device. Physical activity levels and sedentary time were recorded via IPAQ-7. Physical performance was determined using the 30-s sit-and-stand test. There is no previous study in the literature evaluating the relationship between epicardial adipose tissue thickness and sedentary time and physical activity levels in hypertensive patients. With this study, we aim to contribute to the literature by filling this deficiency.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hypertension

Interventions

EPICARDIAL ADIPOSIS TISSUE AND PHYSICAL PERFORMANCE MEASUREMENT

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Volunteering to participate in the study * Being diagnosed with hypertension for at least 6 months * Speaking Turkish * to be able to read and write, * To be between 18-65 years old Exclusion Criteria: * Severe valvular disease * be heart failure * being cardiomyopathy * having chronic kidney disease * being thyroid diseases * active infectious or inflammatory diseases * serious psychiatric illnesses such as panic disorder or major depression

Outcomes

Primary Outcomes

EPICARDIAL ADIPOSIS TISSUE MEASUREMENT

All patients underwent transthoracic echocardiography conducted by a single cardiologist using a Philips HD11XE (Philips Medical Systems) device in the left lateral decubitus position by the standard technique. Epicardial fat thickness was measured in the parasternal long axis imaging window, using the aortic annulus as an anatomical indicator for vertical measurement, and the widest part of the region from the right ventricular free wall to the pericardium at the end of the systole.

Time frame: measured at admission

Secondary Outcomes

PHYSICAL PERFORMANCE

The physical performance of the participants was evaluated with the 30-second sit-and-stand test. While seated in a chair with a seat height of 43.2 cm and a supported back, the patient was asked to stand up and sit down as quickly as possible while crossing his/her hands over his/her chest. The 30-second duration of the test was monitored with a stopwatch and the number of times the participant stood up and sat down was noted. Two trials were performed before the test.