Analgesic Efficacy of Different Volumes in Erector Spinae Plane Block in Single Level Lumbar Spine Fixation

Kafrelsheikh University60 enrolled

Overview

The analgesic efficacy of different volumes in ESPB patients undergoing single-level lumbar spine fixation

The erector spinae plane block (ESPB) its an interfacial plane block for an effective treatment for thoracic neuropathic pain. Currently, compared to the use of opioids, the ESPB has fewer side effects and is safe for patients of all ages having abdominal and thoracic operations .

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Analgesia

Interventions

Bupivacaine 0.25% Injectable SolutionDRUG

Bilateral ultrasound guided in erector spinae plane block by bupivacaine 0.25%

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Aged 18-65 years. 2. Both genders. 3. American Society of Anesthesiologists' (ASA) physical status I or II. 4. Undergoing single level lumbar spine fixation. Exclusion Criteria: 1. Patient refusal. 2. Pregnant females. 3. Renal, lung, heart, or liver disorders. 4. Communication difficulties which might prevent a reliable postoperative assessment. 5. Contraindication to regional anesthesia (bleeding disorder, use of any anticoagulants, local infection, known allergy to local anesthetics). 6. BMI more than 30 kg/m2.

Locations (1)

Kafrelsheikh University

Kafr ash Shaykh, Kafrelsheikh, Egypt

Outcomes

Primary Outcomes

Total morphine consumption

Patients were allowed to receive incremental doses of morphine 3mg intravenously if numerical rating scale pain score will be ≥ then the total amount of morphine will be recorded

Time frame: First 24 hours postoperatively

Secondary Outcomes

Numerical rating scale

Postoperative pain using numerical rating scale (NRS) will be measured at post-anesthesia care unit, from 0 to 10, with 0 representing no pain and 10 representing maximum intolerable pain

Time frame: Up to 48 hours postoperatively

Time to the first rescue analgesic

If numerical rating scale \>4 was observed, rescue analgesia (morphine 3 mg IV) was administered

Time frame: Up to 24 hours postoperatively

Postoperative complications

postoperative nausea and vomiting (PONV), hypotension (mean arterial pressure \< 20% of baseline readings and was managed by ephedrine 5 mg IV and/or normal saline IVI), bradycardia (heart rate \< 60 beats/min and was managed by atropine 0.6 mg IV).

Time frame: Up to 24 hours postoperatively

5-point scale

The degree of patient satisfaction was assessed on a 5-point scale: (0= extremely dissatisfied, 1= unsatisfied, 2= neither satisfied nor unsatisfied, 3= satisfied), and 4= extremely satisfied).

Time frame: Up to 24 hours postoperative

Data from ClinicalTrials.gov

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