Study of MAR001 in Adults With Metabolic Dysfunction

Inclusion Criteria: * Willingness to provide informed consent and comply with the intervention * Women of childbearing potential and men agreeing to use an appropriate method of contraception for the duration of the study * Evidence of metabolic dysfunction at screening (triglyceride levels \> 2.8 mmol/L) Exclusion Criteria: * Any condition which in the opinion of the investigator prevents the participant from complying with study procedures or prevents the participant from completing the study or interferes with the interpretation of study results * Pregnant or breastfeeding mothers * Terminal illness with expected survival of less than 1 year Note: additional inclusion/exclusion criteria may apply, per protocol