The purpose of this study is to investigate the effects of 4 weeks of carbohydrate deprivation (through a ketogenic diet) on hypertrophy signalling after a single bout of exercise in healthy trained male subjects, and the impact on body composition, muscle strength, and blood parameters.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
24
All participants perform a four-day resistance training aimed to stimulate a hypertrophic response.
Subjects allocated to the ketogenic diet arm (KD group) consume less than 50 g of carbohydrates per day.
Subjects allocated to the western diet arm (WD group) consume a standard diet based on 55% of their daily calories from carbohydrates.
Nutex LAB
Padua, Italy
RECRUITINGmammalian target of rapamycin (mTOR) signalling
Measurement of the change in muscle protein anabolic signalling pathway in response to a single bout of resistance exercise by western blot analysis.
Time frame: Change from baseline to 4 weeks
Skeletal muscle mass
Measurement of the change in kilograms of muscle mass via Dexa
Time frame: Change from baseline to 4 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.