To Prevent Type I-II Myoma After TCRM Recurrence by Gonadotropin-releasing Hormone (GnRH )Analogues or Mifepristone

Inclusion Criteria: 1. Age more than 18 years and less than 45 years old, no childbirth requirements in the next 3 years; 2. Type I and II submucosal fibroids diagnosed by ultrasound, and the diameter of them are greater than 3cm; 3. Type I or II submucosal fibroids confirmed by TCRM and no degeneration confirmed pathologically; 4. A MRI test will be done to evaluate the residual submucosal fibroids and calculate the residual fibroid volume after 1 month of surgery; 5. Patients would not had used drugs such as mifepristone and GnRHa 3 months before surgery; 6. Participate in this trial and sign the informed consent form voluntarily . Exclusion Criteria: 1. Combined with congenital uterine malformations such as double uterus, unicornuate uterus, etc; 2. Have fertility requirements within 3 years after surgery; 3. Estrogen-dependent diseases such as adenomyosis and endometriosis; 4. Drugs such as mifepristone or GnRHa have been used before surgery; 5. Mifepristone or GnRHa drug treatment is contraindicated or cannot tolerate TCRM surgery.