This trial hypothesized that novel laser refractive surgery techniques (PRK, LASIK, SMILE) or laser-assisted cataract surgery (FLACAS) could suppress postoperative inflammation and improve recovery in patients by reducing oxidative stress generated by the surgical procedure. It is also intended to verify whether the new laser technology is necessary for clinical use in groups with low antioxidant activity through the detection of antioxidant activity in the eyes of patients.
Study Type
OBSERVATIONAL
Enrollment
132
Cataract surgery includes both conventional and femtosecond laser assisted. Femtosecond-LASIK and SMILE are options for patients to correct myopia.
ChangGungMH
Taoyuan District, Taoyuan City, Taiwan
Nobel Eye Institute
Taipei, Taiwan
Change of Total Antioxidant Capacity (TAC) in tears from Baseline to 1 week after surgery.
Time frame: Before the operation and 1 week after surgery.
Change of Total Antioxidant Capacity (TAC) in tears from Baseline to 1 month after surgery.
Time frame: Before the operation and 1 month after surgery.
Change of Total Antioxidant Capacity (TAC) in tears from Baseline to 3 months after surgery.
Time frame: Before the operation and 3 months after surgery.
Change of Total Antioxidant Capacity (TAC) in tears from Baseline to 6 months after surgery.
Time frame: Before the operation and 6 months after surgery.
Change of Ascorbic Acid (AA) in tears from Baseline to 1 week after surgery.
Time frame: Before the operation and 1 week after surgery.
Change of Ascorbic Acid (AA) in tears from Baseline to 1 month after surgery.
Time frame: Before the operation and 1 month after surgery.
Change of Ascorbic Acid (AA) in tears from Baseline to 3 months after surgery.
Time frame: Before the operation and 3 months after surgery.
Change of Ascorbic Acid (AA) in tears from Baseline to 6 months after surgery.
Time frame: Before the operation and 6 months after surgery.
Change of Total Antioxidant Capacity (TAC) in aqueous humor from Baseline to one day after surgery.
Time frame: During the operation and one day after surgery.
Change of Ascorbic Acid (AA) in aqueous humor from Baseline to one day after surgery.
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Time frame: During the operation and one day after surgery.
Examination of best corrected visual acuity (BCVA).
Time frame: Before the operation.
Examination of uncorrected visual acuity (UCVA).
Time frame: Before the operation.
Examination of uncorrected visual acuity (UCVA).
Time frame: One week after surgery.
Examination of uncorrected visual acuity (UCVA).
Time frame: One month after surgery.
Examination of intraocular pressure (IOP).
Time frame: Before the operation.
Examination of intraocular pressure (IOP).
Time frame: One week after surgery.
Examination of intraocular pressure (IOP).
Time frame: One month after surgery.
Examination of central corneal thickness (CCT).
Time frame: Before the operation.
Examination of central corneal thickness (CCT).
Time frame: One week after surgery.
Examination of central corneal thickness (CCT).
Time frame: One month after surgery.
Examination of axial length (AXL).
Time frame: Before the operation.
Examination of anterior chamber depth (ACD).
Time frame: Before the operation.
Examination of lens thickness (LT).
Time frame: Before the operation.
Examination of manifest refraction.
Time frame: Before the operation.
Examination of manifest refraction.
Time frame: One week after surgery.
Examination of manifest refraction.
Time frame: One month after surgery.
Examination of corneal curvature.
Time frame: Before the operation.
Examination of corneal curvature.
Time frame: One week after surgery.
Examination of corneal curvature.
Time frame: One month after surgery.