To evaluate pain relief from corticosteroid injection with and without anesthetic as well as with variable volume of anesthetic. Pain relief will be measured using the VAS pain score at the time of the injection as well as several time points following the injection to capture pain relief longevity. The investigators intend to evaluate how well the patients tolerate corticosteroid mixtures without anesthetic as well as with different volumes of anesthetic. Primary measure will be the time from procedure when postoperative status is considered success (as measured by global perceived improvement score).
Primary objective is to evaluate pain relief from corticosteroids, Kenalog without anesthetic as well as with different volumes of anesthetic. The investigators will measure the VAS pain score at the time of the injection as well as several time points following the injection. Additionally, the investigators will evaluate how long the injection provided pain relief for the patient. The secondary intend is to evaluate how well the patients tolerate Kenalog mixtures without anesthetic as well as with different volumes of anesthetic by using the VAS pain scale. The investigators hypothesize that patient with lower volume of injection will experience less pain during the procedure and that there will be no statistically significant difference in pain level between the study groups during the study period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
75
Indications, relevant for this study include Kenalog injection for knee pain from osteoarthritis or inflammatory arthritis. A single injection to a patient who has no known allergies to anesthetic or corticosteroids would be administered during a scheduled clinical visit.
Florida Orthopaedic Institute
Tampa, Florida, United States
Injection for Knee Pain
Visual Analogue Scale (VAS)
Time frame: Prior to procedure (in office)
Injection for Knee Pain
Visual Analogue Scale (VAS)
Time frame: Immediate post procedure (in office)
Injection for Knee Pain
Visual Analogue Scale (VAS)
Time frame: 2 minutes post procedure (in office)
Injection for Knee Pain
Visual Analogue Scale (VAS)
Time frame: Day 1 post procedure (phone interview)
Injection for Knee Pain
Visual Analogue Scale (VAS)
Time frame: Day 14 post procedure (through EDC)
Injection for Knee Pain
Visual Analogue Scale (VAS)
Time frame: Day 42 post procedure (in office)
Injection for Knee Pain
Visual Analogue Scale (VAS)
Time frame: Day 84 post procedure (through EDC)
Assessment of Knee Pain
Global Perceived Improvement
Time frame: Immediate Post-op (in office)
Assessment of Knee Pain
Global Perceived Improvement
Time frame: Day 1 post procedure (phone interview)
Assessment of Knee Pain
Global Perceived Improvement
Time frame: Day 42 post procedure (in office)
Assessment of Knee Pain
Global Perceived Improvement
Time frame: Day 84 post procedure (through EDC)
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