The Movement Disorders Society (MDS) Unified Parkinson's Disease Rating Scale (UPDRS) Part III (MDS-UPDRS III) is the primary assessment method for motor symptoms in Parkinson's disease patients. Currently, movement disorder specialists conduct semi-quantitative scoring, which entails limitations such as subjectivity, weak sensitivity, and a limited number of professional physicians. This study, based on machine vision, establishes gold standard labels according to expert scoring. By using machine learning, we develop a machine rating model and compare the model's performance with gold standard rating and general clinical rating to investigate the accuracy of machine vision-based MDS-UPDRS III machine rating.
Study Type
OBSERVATIONAL
Enrollment
871
Patients' performance of MDS-UPDRS III will be recorded.
Center for Movement Disorders, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University
Beijing, Beijing Municipality, China
NOT_YET_RECRUITINGBeijing Hospital, Neurology Department
Beijing, Beijing Municipality, China
NOT_YET_RECRUITINGDepartment of Neurology, Fujian Medical University Union Hospital
Fuzhou, Fujian, China
NOT_YET_RECRUITINGDepartment of Neurology, Guangdong Neuroscience Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences
Guangzhou, Guangdong, China
NOT_YET_RECRUITINGDepartment of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
NOT_YET_RECRUITINGDepartment of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
NOT_YET_RECRUITINGDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China
RECRUITINGDepartment of Neurology, West China Hospital, Sichuan University
Chengdu, Sichuan, China
NOT_YET_RECRUITINGACC0 of machine rating vs gold standard rating
The accuracy rate when machine rating equals gold standard rating.
Time frame: 1 day
ACC1 of machine rating vs gold standard rating
The accuracy rate when machine rating equals the range of gold standard rating plus or minus one.
Time frame: 1 day
Weighted kappa of machine rating vs gold standard rating
The weighted kappa when machine rating equals gold standard rating.
Time frame: 1 day
Lin's CCC of machine rating vs gold standard rating
The Lin's Concordance Correlation Coefficient when machine rating equals gold standard rating.
Time frame: 1 day
Accuracy rate of machine rating vs general clinical rating
Comparing the absolute residuals between machine rating and the gold standard rating with the absolute residuals between general clinical raitng and the gold standard rating.
Time frame: 1 day
Accuracy rate of machine facilitated rating vs general clinical rating
Comparing the absolute residuals between machine facilitated rating and the gold standard rating with the absolute residuals between general clinical raitng and the gold standard rating.
Time frame: 1 day
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