This is a prospective observational pilot study of suitability of autonomic monitoring via the VU-AMS device for prediction of neurocardiogenic syncope (NCS) in children referred to cardiopulmonary exercise testing (CPET) for a diagnosis of syncope. The study population is children referred for CPET to evaluate for neurocardiogenic syncope. The purpose is to describe autonomic function during rest and exercise and determine the positive predictive value of autonomic function measurements against the gold standard for diagnosis of neurocardiogenic syncope, the CPET. Children presenting for CPET with chest pain or who are status post orthotopic heart transplantation will serve as positive and negative controls respectively.
Study Type
OBSERVATIONAL
Enrollment
40
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
Autonomic data respiratory sinus arrhythmia among patients with chest pain
Subjects will wear an ambulatory monitor during testing
Time frame: Data collected throughout cardiopulmonary exercise testing. Up to 90 minutes.
Autonomic data respiratory sinus arrhythmia among patients with syncope
Subjects will wear an ambulatory monitor during testing
Time frame: Data collected throughout cardiopulmonary exercise testing. Up to 90 minutes.
Autonomic data respiratory sinus arrhythmia among patients post heart transplant
Subjects will wear an ambulatory monitor during testing
Time frame: Data collected throughout cardiopulmonary exercise testing. Up to 90 minutes.
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