EXecution of Trans-Esophagus Echo Cardiogram in CardioPulmonary Resuscitation for Patients With Out-of-hospital Cardiac Arrest

Far Eastern Memorial Hospital132 enrolled

Overview

The purpose of this single center, randomized clinical control trial is to determine that changing chest compression site during cardiopulmonary resuscitation according to the examination of the TEE could increase the level of end-tidal CO2, which represents the quality of cardiopulmonary resuscitation, or not in adult patients with non-traumatic out-of-hospital cardiac arrest while comparing to those who don't receive examination of transesophageal echocardiography during cardiopulmonary resuscitation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

132

Conditions

Out-Of-Hospital Cardiac Arrest

Interventions

transesophageal echocardiography examination during cardiopulmonary resuscitation

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age ≥ 20 years-old 2. Out-of-hospital cardiac arrest 3. Non-trauma Exclusion Criteria: 1. Obvious signs of death appears, such as separation of head and body, rigor mortis, livor mortis, cankered corpse......etc. 2. Family members clearly express the willing of do not attempt resuscitation or patients who have registered advance care planning not to attempt resuscitation. 3. Patients not suitable for transesophageal ultrasound, such as patients with esophageal tumor, those whose probe cannot be placed......etc. 4. Received Extracorporeal CPR. 5. Achieving sustained ROSC before ED arrival

Outcomes

Primary Outcomes

Rate of sustained return of spontaneous circulation (ROSC)

successful restoration and maintenance of a patient's heartbeat and blood circulation after undergoing cardiopulmonary resuscitation (CPR) for at least 20 minutes

Time frame: 20 minutes after ROSC

Secondary Outcomes

Rate of any return of spontaneous circulation

successful restoration and maintenance of a patient's heartbeat and blood circulation after undergoing cardiopulmonary resuscitation (CPR)

Time frame: 1 minutes after ROSC

Rate of survival to ICU admission

Successful restoration and stabilization of a patient's heartbeat and circulation, enabling safe transfer to the ICU.

Time frame: 48 hours after ROSC

Rate of survival to discharge

successful restoration and maintenance of a patient's heartbeat and blood circulation and able to complete treatment course till discharge

Time frame: 6 months after ROSC

Rate of discharge with favorable neurological outcomes

using cerebral performance category score to measure neurologic outcomes of the patient at the time while patient's discharge. CPC1 and 2 are consider as favorable neurological outcomes, CPC3 and 4 are consider as unfavorable neurological outcomes

Time frame: 6 months after ROSC

end-tidal carbon dioxide (EtCO2)

measuring end-tidal carbon dioxide during resuscitation

Time frame: During resuscitation