The goals of this pilot study are to assess the presence of harmful germs for gums and to assess oral health in adults with autism spectrum disorder.
Participants or their tutors will fulfill a form with general health information and daily habits. Investigators will : * collect saliva, gum fluid and/ or dental plaque to characterise germs * assess gum health and oral hygiene * register decays, filled and missing teeth.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
37
Non-invasive sampling of dental plaque, crevicular fluid and/or saliva, using an examination probe, paper tips and saliva swabs
CHRU Brabois
Vandœuvre-lès-Nancy, France
Presence of periodontopathogenic bacteria (harmful for gums)
Technique used = Polymerase Chain Reaction (PCR) Measure unit = Colony-Forming Unit (CFU)
Time frame: Collection on Day 1
Assessment of the presence of parasites Entamoeba gingivalis subtype 1 (ST1) and subtype 2 (ST2) and Trichomonas tenax
Technique = Polymerase Chain Reaction (PCR) Unit = Colony-Forming Unit (CFU)
Time frame: Collection on Day 1
Assessment of the periodontal status of patients with Autism Spectrum Disorder
Index used = the Dutch Periodontal Index 0 = minimum value, better outcome 4 = maximum value, worse outcome
Time frame: Day 1
Assessment of the dental condition
Dental data will be collected using the Decay-Missing-Filled/Teeth (DMFT) score 0 = minimum value, best outcome 28 = maximum value, worst outcome
Time frame: Day 1
Assessment of oral hygiene
Oral hygiene will be assessed using the Silness and Löe plaque index and the lifestyle questionnaire 0 = minimum value, best outcome 3 = maximum value, worst outcome
Time frame: Day 1
Collection of data about lifestyle habits (oral and dental hygiene, diet, activity, etc.) and drug treatments that may influence the clinical parameters observed
Data collection via a form fulfilled by the participant or the patient's legal guardian
Time frame: Before samples collection and clinical examination
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