The aim of this study is to assess the ocular parameters of drowsiness in patients with diagnosed Obstructive Sleep Apnea Syndrome through objective methods of ocular imaging and subjective evaluation methods (questionnaire)
This is a single-center prospective comparative observational study. One hundred patients with drowsiness that will be examined in the Sleep Clinic of Alexandroupolis University Hospital, aged between18-70 years old, with Distance Uncorrected Visual Acuity ≥ (dUVA): 5/10 will be recruited. They will be separated into two groups, one consisting of patients with diagnosed Obstructive Sleep Apnea and one without this diagnosis, according to the Epworth Sleepiness Scale - ESS, which is a valid tool for quantifying daily sleepiness. A 10-minute video in a foreign language (not English or Greek) with greek subtitles will be presented to them and a questionnaire will follow to assess the level of concentration during the video (the subtitles are crucial to understanding the video's plot). The video will be displayed in a 11.6" screen with resolution of 1920x1080 pixels, at 70 cm patient-to-screen distance. The patients' eyes will be recorded during the video with a Raspberry Pi Camera Module IR-CUT v2 (5MP,1080p) with 2 IR LED lights, connected to a Raspberry Pi 3 model v1.2, operating at the original resolution of 1080×1920, at 20 cm patient-to-camera distance and an algorithm will be developed to analyze the following parameters: 1. The complete and incomplete blinks defined by the "length of palpebral fissure-to-iris diameter" ratio, 3. Length of palpebral fissure of both eyes.
Study Type
OBSERVATIONAL
Enrollment
100
A 10-minute video in a foreign language (not English or Greek) with greek subtitles will be presented and a questionnaire will follow to assess the level of concentration during the video
Democritus University of Thrace
Alexandroupoli, Evros, Greece
RECRUITINGTotal number of blinks during the 10-minute video
The total number of blinks during the 10-minute video. Complete blinks are defined by the "length of palpebral fissure-to-iris diameter" ratio.
Time frame: 1 week
Total number of complete blinks during the 10-minute video
The total number of complete blinks during the 10-minute video. Complete blinks are defined by the "length of palpebral fissure-to-iris diameter" ratio.
Time frame: 1 week
Total number of incomplete blinks during the 10-minute video
The total number of incomplete blinks during the 10-minute video. Incomplete blinks are defined by the "length of palpebral fissure-to-iris diameter" ratio.
Time frame: 1 week
Number of total blinks for each minute
Number of total blinks for each minute of the 10-minute video
Time frame: 1 week
Number of complete blinks for each minute
Number of complete blinks for each minute of the 10-minute video
Time frame: 1 week
Number of incomplete blinks for each minute
Number of incomplete blinks per minute for each minute of the 10-minute video
Time frame: 1 week
Total blinks per minute
Total blinks per minute during the 10-minute video
Time frame: 1 week
Complete blinks per minute
Complete blinks per minute during the 10-minute video
Time frame: 1 week
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Incomplete blinks per minute
Incomplete blinks per minute during the 10-minute video
Time frame: 1 week
Length of palpebral fissure of both eyes
The distance between the upper eyelid margin and the lower eyelid margin (ie. the vertical dimension of the palpebral fissure) for each frame
Time frame: 1 week
Fixations to the area of interest
Number of fixations to the area of interest (subtitles)
Time frame: 1 week
Fixation duration
Mean fixation duration (duration of fixation per video per participant)
Time frame: 1 week
Reading time
The absolute reading time (the sum of the duration of all fixations and saccadic movements in the area of focus starting from the first fixation)
Time frame: 1 week
Participant's dedication time to the area of focus
The percentage of time that each participant dedicates to the area of focus depending on the time of subtitle exposure (eg. subtitle reading time/overall subtitle exposure= 2500 msec/3000 msec=83%)
Time frame: 1 week
Rereadings
Rereadings: the number of fixations/seccadic movements to the area of focus after the first reading (indicating of subtitlte interpretation difficulty or extended subtitle exposure time).
Time frame: 1 week