Renal Doppler in Pediatric Patients With Idiopathic Nephrotic Syndrome

Tanta University60 enrolled

Overview

The use of the renal resistive index in pediatric patient with idiopathic nephrotic syndrome to detect steroid resistance and to use it as a prognostic instrument of the progression of the disease.

Renal Doppler will be done for all children in supine and lateral positions using Toshiba Aplio ultrasound machine and renal resistive index will be measured (peak systolic velocity- end diastolic velocity/ peak systolic velocity) at diagnosis, after one month, 3 months and 6months, in which these values will be obtained by the ultrasound machine based on the computer algorithm. Also the kidneys will be scanned firstly for length, width, cortical thickness and echogenicity.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Nephrotic Syndrome

Interventions

renal dopplerDEVICE

Toshiba Aplio ultrasound machine and renal resistive index will be measured (peak systolic velocity- end diastolic velocity/ peak systolic velocity

Eligibility

Sex: ALLMin age: 1 YearMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pediatric patients with primary nephrotic syndrome aged from 1 to 18 years Exclusion Criteria: * \- Patients with congenital nephrotic syndrome. * Patients with secondary causes of nephrotic syndrome.

Locations (1)

Sara Mabrouk Mohamed Elghoul

Tanta, Egypt

Outcomes

Primary Outcomes

detection of steroid resistance in pediatric patients with idiopathic nephrotic syndrome

measurement of renal resistive index and detection of steroid sensitivity

Time frame: 6 weeks

Secondary Outcomes

progression of nephrotic syndrome

frequent measurement of renal resistive index and using it as prognostic factor

Time frame: six months

Data from ClinicalTrials.gov

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