Determining Individualized Cancer Therapy in Pancreatic Cancer

Medical College of Wisconsin1,000 enrolled

Overview

This is a non-therapeutic exploratory observational precision oncology study designed to collect and analyze data that demonstrate the clinical efficacy and tolerability of personalized treatments based on molecular tumor profiling assessments (i.e., matched therapy) in adult pancreatic cancer patients. Patient medical records, obtained both retrospectively and prospectively, will be examined for results of molecular profiling obtained through standard of care testing to help understand how well molecular testing might predicts response to therapy. Patient demographic and outcome parameters to be evaluated include, but are not limited to, tumor response, time to treatment failure, patient survival, and toxicity.

Study Type

OBSERVATIONAL

Enrollment

1,000

Conditions

Pancreatic Neoplasms

Interventions

Targeted TherapyOTHER

Approved interventions based on the subject's genomic profile will be provided to investigators for consideration for anti-tumor therapy.

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥18 years. * Pathologically confirmed pancreatic cancer. * Ability to understand a written informed consent document and the willingness to sign it Exclusion Criteria: * Age \<18 years. * Primary cancer diagnosis other than pancreatic cancer.

Outcomes

Primary Outcomes

Number of Subjects Receiving Targeted Therapy

This measure is the number of study subject's whose treating physician prescribes and subsequently receives the therapeutic recommendation of the Molecular Tumor Board.

Time frame: 5 years