A retrospective, non-interventional cohort study was used to address the study objectives. This study aimed to provide a better understanding of real-world healthcare resource utilization (HRU) and healthcare reimbursement costs associated with chimeric antigen receptor modified T cell (CAR-T) therapy among patients with DLBCL.
Study Type
OBSERVATIONAL
Enrollment
1,031
Novartis
East Hanover, New Jersey, United States
Number of hospital admissions in the CAR-T IP and CAR-T OP cohorts
Time frame: Up to approximately 10 months
Number of inpatient (IP) days in the CAR-T IP and CAR-T OP cohorts
Time frame: Up to approximately 10 months
Number of intensive care unit (ICU) stays in the CAR-T IP and CAR-T OP cohorts
Time frame: Up to approximately 10 months
Number of ICU days in the CAR-T IP and CAR-T OP cohorts
Time frame: Up to approximately 10 months
Number of emergency room (ER) visits in the CAR-T IP and CAR-T OP cohorts
Time frame: Up to approximately 10 months
Number of outpatient (OP) visits in the CAR-T IP and CAR-T OP cohorts
Time frame: Up to approximately 10 months
Percentage of patients in the CAR-T IP and CAR-T OP cohorts with any IP admission
Time frame: Up to approximately 10 months
Percentage of patients in the CAR-T IP and CAR-T OP cohorts with ER visits
Time frame: Up to approximately 10 months
Percentage of patients in the CAR-T IP and CAR-T OP cohorts with OP services
Time frame: Up to approximately 10 months
Total pre-infusion healthcare reimbursement costs in the CAR-T IP and CAR-T OP cohorts
Time frame: Up to approximately 10 months
Total CAR-T infusion-related healthcare reimbursement costs in the CAR-T IP and CAR-T OP cohorts
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Time frame: Up to approximately 10 months
Total post-infusion healthcare reimbursement costs in the CAR-T IP and CAR-T OP cohorts
Time frame: Up to approximately 10 months
Cumulative percentage of patients admitted in the hospital during the first month after CAR-T OP infusion
Time frame: Up to approximately 10 months
Percentage of patients hospitalized each day during the first month after CAR-T infusion among the CAR-T IP and OP cohorts
Time frame: Up to approximately 10 months
Main cause of IP admission/re-admission among the CAR-T IP and OP cohorts, up to three months following infusion
Time frame: Up to approximately 10 months
Percentage of patients with AEs
Time frame: Up to approximately 10 months
Healthcare reimbursement costs per AE event
Time frame: Up to approximately 10 months
Number of IP admissions in the overall CAR-T and allo-HSCT cohorts
Time frame: Up to approximately 10 months
Number of IP days in the overall CAR-T and allo-HSCT cohorts
Time frame: Up to approximately 10 months
Number of OP visits in the overall CAR-T and allo-HSCT cohorts
Time frame: Up to approximately 10 months
Number of ER visits in the overall CAR-T and allo-HSCT cohorts
Time frame: Up to approximately 10 months
Total healthcare reimbursement costs in the overall CAR-T and allo-HSCT cohorts
Time frame: Up to approximately 10 months
Main cause of IP admission/re-admission among the CAR-T IP and OP cohorts
Time frame: Up to approximately 10 months
Number of intensive care unit (ICU) stays in the overall CAR-T and allo-HSCT cohorts
Time frame: Up to approximately 10 months
Number of ICU days in the overall CAR-T and allo-HSCT cohorts
Time frame: Up to approximately 10 months