We conducted a retrospective observational cohort study assessing the relationship between regular bathing using 2% CHG wipes every other day and the occurrence of central line-associated infections (CLABSI) in patients within the medical intensive care unit (MICU).
This study defined the post-intervention period as July 1, 2017, to June 30, 2022. During this period, one of the three medical intensive care units (MICUs) in NTUH implemented chlorhexidine gluconate (CHG) bathing as part of their daily care routine (CHG group). This decision was made in response to a higher incidence rate of vancomycin-resistant Enterococcus (VRE) bacteremia observed in that particular MICU during the preceding six months (pre-intervention period: January 1, 2017, to June 30, 2017), compared to the other two MICUs. The remaining two MICUs continued to provide usual care, which involved bathing patients with towels soaked in water and soap on a daily basis.
Study Type
OBSERVATIONAL
Enrollment
6,930
The procedure involved pouring an entire bottle (200ml) of 2% CHG solution (PBF Biotech, Taipei, Taiwan) onto a pre-packed set of eight single-use cotton wipes before each bathing session. A minimum of six wipes were required to thoroughly cover the entire body, including the bilateral upper and lower extremities, front and back of the trunk, perineum, and buttocks.
National Taiwan University Hospital
Taipei, Taiwan
central line-associated bloodstream infections
the incidence rate of intensive care unit acquired central line-associated bloodstream infections
Time frame: Will be surveyed retrospectively through the study period (January 2017 to June 2022)
multidrug-resistant organisms bacteremia
the incidence of CLABSIs with blood cultures positive for multidrug-resistant organisms
Time frame: Will be surveyed retrospectively through the study period (January 2017 to June 2022)
ICU length of stay
the total duration of the patient's ICU stay (days)
Time frame: Will be surveyed retrospectively through the study period (January 2017 to June 2022)
hospital length of stay
the total duration of the patient's hospital stay (days)
Time frame: Will be surveyed retrospectively through the study period (January 2017 to June 2022)
ICU mortality
whether the patient has died during their stay in the ICU
Time frame: Will be surveyed retrospectively through the study period (January 2017 to June 2022)
hospital mortality
whether the patient has died during their stay in the hospital
Time frame: Will be surveyed retrospectively through the study period (January 2017 to June 2022)
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