Accuracy of Pulse Oximeters in Profound Hypoxia

Inclusion Criteria: * Subject is in good general health with no evidence of any medical problems. * Subject is fluent in both written and spoken English. * Subject provided written informed consent and is willing to comply with the study procedures. * Subject is willing to have their skin color assessed. Exclusion Criteria: * Subject is obese with a BMI over 30. * Subject has a known history of heart disease, lung disease, kidney or liver disease. * Subject has asthma, sleep apnea, or uses a CPAP. * Subject has diabetes. * Subject has a clotting disorder, anemia, or in the opinion of the investigator, they would be unsuitable for participation. * Subject has any other serious system illness. * Subject is a current smoker. * Subject has any injury, deformity, or abnormality at the sensor sites that, in the opinion of the investigator, would interfere with the sensors working correctly. * Subject has a history of fainting or vasovagal response. * Subject has a sensitivity to local anesthesia. * Subject has Raynaud's disease. * Subject has unacceptable collateral circulation based on an exam by the investigator. * Subject is pregnant, lactating, or trying to get pregnant. * Subject is unable or unwilling to provide informed consent or is unable or unwilling to comply with the study procedures. * Subject has any other condition, which in the opinion of the investigator, would make them unsuitable for the study.