Preclinical Research of mμSORS for Noninvasive Blood Glucose Detection

Inclusion Criteria: * 1\. Subjects with type 2 diabetes mellitus; * 2\. Age ≥ 18 years; * 3\. There are no scars, obvious pigmentation and other factors that interfere with the detection of the palm skin to be tested; * 4\. Fully understand the nature, significance, possible benefits, possible inconveniences or potential risks of this research, and should also understand the research procedures, be willing to complete the entire research process, and provide written consent form. Exclusion Criteria: * 1\. Type 1 diabetes, monogenic diabetes, pancreatic damage, or secondary diabetes of other causes should be excluded; * 2\. Severe structural heart disease, such as congenital heart disease, rheumatic heart disease, hypertrophic or dilated cardiomyopathy, chronic congestive heart failure (NYHA≥III); acute myocardial infarction within 12 months before enrollment; history of severe liver or kidney dysfunction(MDRD eGFR\< 60 ml/min/1.73m2); and mental disorders, etc.; * 3\. With a history of acute complications of diabetes within 3 months before enrollment; or severe chronic complications of diabetes; * 4\. Alcohol dependency or drug abuse; * 5\. Those who have participated in clinical trials of other drugs within 3 months before screening (since the last visit of the previous trial); * 6\. Pregnancy or lactation period; * 7\. Difficulty in venous blood collection or blood-injection-injury phobia; * 8\. Other circumstances that the investigator considers inappropriate to participate in the study.