The purpose of this study is to analyze AMH levels in patients with prolonged FHA (more than 2 years). Based on previous studies, we can assume that prolonged FHA may mimic a condition of primary hypogonadotropic hypogonadism, due to a lasting interruption of gonadotropin release. Furthermore, after the resumption of the spontaneous menstrual cycle, we will reanalyze AMH levels, which we hypothesize to find higher. If our hypotheses are confirmed correct, we could support the thesis that AMH is not a good index of ovarian reserve in patients with functional hypothalamic amenorrhea.
Study Type
OBSERVATIONAL
Enrollment
50
venous sampling
Rosanna Apa
Rome, Italy
RECRUITINGAMH assay
Check serological AMH levels in patients with FHA for at least 2 years and compare them with AMH levels in healthy women.
Time frame: 12 months
To correlate AMH levels with other parameters
Correlate serologic AMH levels with antral follicle count (AFC). Verify serologic AMH levels in previously FHA patients after resumption of spontaneous menstruation, i.e., at 6 months
Time frame: 12 months
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