The goal of this clinical trial is to compare the effects of protein consumption before sleep or immediately after exercise during 12 weeks of resistance exercise training in older adults. The main questions it aims to answer are: Are there differences in muscle growth or strength during 12 weeks of resistance training when 40 grams of protein is consumed either before sleep or immediately after exercise? Are there differences in cognitive performance during 12 weeks of resistance training when 40 grams of protein is consumed either before sleep or immediately after exercise? This study is a randomized double-blind placebo-controlled study. Participants will be randomly allocated into 1 of 3 groups. All three groups will perform the same 12-week resistance exercise training program two times per week and consume 40 g of protein: 1) Immediately post-exercise, 2) 30 minutes prior to sleep, or 3) no supplemental protein (control). Test of muscle growth and strength, and cognitive performance will be measure before, during, and after the exercise training program. Researchers will compare the 3 conditions to determine if consume protein after exercise or before sleep during 12 weeks of resistance exercise training affects muscle growth and strength, and cognitive performance.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
32
Florida State University
Tallahassee, Florida, United States
Muscle thickness
Change in muscle thickness of the quadriceps muscles in centimeters from week 0 (baseline) to week 6 (midpoint) to week 12 (end of study).
Time frame: Week 0, 6, and 12
Maximum muscular strength
Changes in strength of the chest press and leg press exercises in kilograms from week 0 (baseline) to week 6 (midpoint) to week 12 (end of study).
Time frame: Week 0, 6, and 12
Muscle power
Changes in power (Watts) during a sit-to-stand task from week 0 (baseline) to week 6 (midpoint) to week 12 (end of study).
Time frame: Week 0, 6, and 12
Cognitive performance
Changes in the number of correct responses during the digit symbol substitution task and pattern comparison tests from week 0 (baseline) to week 12 (end of study).
Time frame: Week 0 and 12
Measures associated appetite
Changes in subjective measures of hunger, satiety, and desire to eat on a 0-100 millimeter (higher values indicating stronger feeling) visual analog scale from week 0 (baseline) to week 6 (midpoint) to week 12 (end of study).
Time frame: Week 0, 6, and 12
Total sleep time
Changes in actigraphy watch measured total sleep time in hours from week 0 (baseline) to week 12 (end of study).
Time frame: Week 0 and 12
Sleep latency
Changes in actigraphy watch measured sleep latency in minutes from week 0 (baseline) to week 12 (end of study).
Time frame: Week 0 and 12
Measures associated with sleep
Changes in actigraphy watch measured sleep efficiency (ratio of time spent asleep to the time spent in bed) in percentage from week 0 (baseline) to week 12 (end of study).
Time frame: Week 0 and 12
Nitrogen balance
Changes in urinary nitrogen balance (grams per day) from week 0 (baseline) to week 12 (end of study).
Time frame: Week 0 and 12
Free insulin-like growth factor 1
Changes in plasma free insulin-like growth factor 1 concentration (nanogram per deciliter) from week 0 (baseline) to week 12 (end of study).
Time frame: Week 0 and 12
Mood
Changes in the Profile of Mood State rating scale categories of tension, depression, anger, fatigue, confusion, vigor, and total mood disturbance from week 0 (baseline) to week 12 (end of study) via a 1 to 5 scale (higher score indicates stronger feeling).
Time frame: Week 0 and 12
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