The study is aimed to phenotype with cardiac MRI the physiological effects of ketone esters on the heart. Patients with heart failure will be recruited and given ketone esters or placebo in a randomized fashion. Cardiac MRI will be performed at baseline and after 12weeks follow up.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
50
Added to water or lemonade 3 times per day.
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Cardiovascular Innovation Research Center
Cleveland, Ohio, United States
Change in Left Ventricular Ejection Fraction
Measured with cardiac MRI the left ventricular ejection fraction at two points and then delta is calculated
Time frame: Pre-intervention and up to 12 weeks after intervention
Change in Creatine concentration
Measured with cardiac MRI the creatine concentration at two points and then delta is calculated
Time frame: Pre-intervention and up to 12 weeks after intervention
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