The goal of this study is compare the effect of hybrid closed loop system (HCL) for automatic insulin dosing treatment on the glycemic control of type 1 diabetes (T1D) in patient with different initial glycated hemoglobin.
Rationale for the Study: According to our hypothesis, even T1D patients with an initially optimal glucose level should benefit from this treatment method in the form of a reduction in glycemic variability. There are very few clinical studies from real practice in a larger group of patients.
Study Type
OBSERVATIONAL
Enrollment
120
type of hybrid close loop insulin delivery system
type of hybrid close loop insulin delivery system
Lucie Radovnická
Ústí nad Labem, Czechia
RECRUITINGglycated hemoglobin
The difference and changes in glycated hemoglobin (HbA1c, % DCCT \[mmol/mol\]) between baseline and at 12 months after using HCL.
Time frame: 12 month
tim spent in TIR
changes in percentage of time in range (%TIR, 70-180 mg/dL \[3.9-10.0 mmol/L\])
Time frame: 12 month
time spent in hypoglycemia
percentage of time spent in hypoglycemia (%TBR, \<70 mg/dL \[\<3.9 mmol/L\] and \<54 mg/dL \[\<3.0 mmol/L\])
Time frame: 12 month
time spent in hyperglycemia
percentage of time spent in hyperglycemia (%TAR, \>180 mg/dL \[\>10.0 mmol/L\] and \>250 mg/dL \[\>13.9 mmol/L\])
Time frame: 12 month
glycemic variability
glycemic variability expressed as the percentage coefficient of variation (%CV) and standard deviation (SD)
Time frame: 12 m,onth
mean sensor glucose value
mean sensor glucose value
Time frame: 12 month
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