Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure

Inclusion Criteria: * Male or female adults aged between 18 and 55 years included * Subject with a habit of using little or no sunscreen products with low protection index (SPF \< 25) during sun exposure. * Subject's commitment to have a self-reported sun exposure of at least 3 hours per day for the 5 days of their last week of vacation * Subjects agreeing not to expose themselves to UVs (natural or artificial) before the planned outdoor sun exposure period Exclusion Criteria: 1. \- Criteria related to the population: * Smoker of more than 10 cigarettes per day containing nicotine, paper and/or electronic cigarette equivalent * Subject having received on study areas artificial UV exposure or excessive, prolonged, and unprotected exposure to natural sunlight within the 4 weeks before the inclusion visit or planning one during the study * Subject having performed excessive and prolonged physical activity (e.g. trail, long distance running, race…) within 7 days before the inclusion visit 2. \- Criteria related to the diseases / skin condition: * Subject with a known history of photosensitivity (toxic, allergic) * Subject with a known personal or family history of skin cancer * Subject having hereditary or acquired disorders of hemostasis. 3. \- Criteria related to the treatments and/or products: * Physical treatment (radiotherapy, phototherapy, chemical peeling, laser, ...) on the study area within 4 weeks before the inclusion visit or planned during the study. * Systemic or topical treatment applied on the study area (e.g. anti-allergic, anti-inflammatory treatment) within two weeks before the inclusion visit, ongoing or planned during the study and likely to interfere with the study according to the investigator's assessment * Use of anti-aging products (containing retinoids and / or α-hydroxy acids) on the target areas (face and/or forearms) in the 2 weeks before the inclusion visit. * Systemic or topical treatment with photosensitizing or phototoxic potential (NSAIDs, antihistamines, psychotropic drugs, antidepressants, anti-migraine drugs, cyclines, quinolone, antibiotics, beta-blockers, etc.), taken or applied to the study area within the previous weeks, ongoing or planned during the study, and likely to interfere with the study according to the investigator's assessment * Subject taking creatine dietary supplements and/or practicing prolonged fasting