The Role of Point-of-care Polymerase Chain Reaction in Managing Nosocomial Pneumonia

Iuliu Hatieganu University of Medicine and Pharmacy60 enrolled

Overview

The study compares a device that is used for the detection of bacteria and MDR pathogens from skin, soft tissue and nose with the gold-standard (microbiological lab). It is a novel use for this device because it has been used in samples from the lower-respiratory tract.

The purpose of this study is to find out if a POC-PCR device can be use in the diagnosis of hospital acquired pneumonia and ventilation-associated pneumonia.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Nosocomial Pneumonia

Interventions

no interventionDIAGNOSTIC_TEST

no intervention

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients that are admitted for at least 48 hours * radiological findings typical for pneumonia * signs of infection Exclusion Criteria: * patient or patient relatives doesn't accept to enter the study

Locations (1)

Spitalul Clinic Judetean de Urgenta Cluj

Cluj-Napoca, Cluj, Romania

Outcomes

Primary Outcomes

To determine the sensibility and specificity of the device GeneXpert in diagnosis of pneumonia

Comparison between device and gold standard

Time frame: 4 years

Utility of POC-PCR in managing pneumonia

Decision making in pneumonia management

Time frame: 4 years

Data from ClinicalTrials.gov

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