The Role of Autoimmunity and Obesity in Polycystic Ovary Syndrome

Sohag University90 enrolled

Overview

The goal of the study is to detect autoantibodies in the serum of the women with PCOS and evaluate the obesity markers to investigate the the role of autoimmunity and obesity in PCOS

Study Type

OBSERVATIONAL

Enrollment

Conditions

Polycystic Ovary Syndrome

Eligibility

Sex: FEMALEMin age: 12 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients diagnosed with PCOS according to the Rotterdam (2003) criteria. Exclusion Criteria: * Patients with other causes of hyperandrogenism as congenital adrenal hyperplasia, androgen-secreting tumors, Cushing's syndrome, hyperprolactinemia, virilizing ovarian or adrenal tumors and those taking drugs affecting insulin resistance, such as estrogens, oral contraceptives and corticosteroids during the previous three months before the study.

Locations (1)

Sohag university

Sohag, Egypt

Outcomes

Primary Outcomes

measuring serum anti-ovarian, anti-nuclear, anti-double stranded and anti-thyroid antibodies

Theses markers will be measured using ELISA technique

Time frame: 3 months after recruitment

Central Contacts

Ola AH Hamed, Assistant lecturer

CONTACT

2001061137434 ola.hamed@med.sohag.edu.eg

Data from ClinicalTrials.gov

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