This project aims to explore the relationship between healthy lifespan and nutrition through a 10-year longitudinal study in Zhejiang Province. The cohort will include individuals in a wide range of age groups. The demographic, diet, lifestyle information, health status, and corresponding bio-samples will be collected carefully. It will give a deeper insight to the relation between nutrition and healthy aging and longevity. Ultimately, this research will contribute to evidence-based nutrition interventions to improve health outcomes and enhance quality of life.
This project aims to elucidate the relationship between healthy lifespan and nutrition through the establishment of a large-scale cohort of participants and longitudinal follow-ups spanning around 10 years in Zhejiang Province. The cohort will comprise individuals in a wide range of age groups starting at 6 years old. The participants will provide demographic information, anthropometry measurements, detailed diet, lifestyle data and health status, including 3-day dietary records and long-term food intake frequency recalls. Integrated with previous information, diverse bio-samples will also be collected to establish a multi-dimensional biobank. It will give a deeper insight to the relation between nutrition and healthy aging and longevity. Ultimately, this research will contribute to the development of evidence-based nutrition designed to improve health outcomes and enhance the quality of life for individuals of all ages.
Study Type
OBSERVATIONAL
Zhejiang Provincial Center for Disease Control and Prevention
Hangzhou, Zhejiang, China
Westlake University
Hangzhou, Zhejiang, China
Occurrence of cardio-metabolic diseases
The investigators will track for occurrence of cardio-metabolic diseases by follow-up surveys collected by the Zhejiang Center for Disease Control and Prevention.
Time frame: up to 10 years
Changes in fasting blood glucose
Fasting glucose will be examined in mmol/L.
Time frame: Every other year， up to 10 years
Changes in fasting blood HbA1c
Fasting blood HbA1c will be examined in %
Time frame: Every other year， up to 10 years
Changes in fasting lipid metabolism
Triglyceride, cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol will be examined in mmol/L.
Time frame: Every other year， up to 10 years
Changes in fasting blood highly sensitive C-reactive protein (CRP)
CRP will be examined in mg/L.
Time frame: Every other year， up to 10 years
Changes in body mass index
Body mass index (BMI) will be calculated in kg/m\^2
Time frame: Every other year， up to 10 years
Changes in blood pressure
Blood pressure, including systolic and diastolic blood pressure, will be measured in mmHg
Time frame: Every other year， up to 10 years
Changes in gut microbiome profiling
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16S rRNA and/or shotgun metagenomic sequencing will be performed in stool samples.
Time frame: Every other year， up to 10 years