The aim of this retrospective study is to investigate the relationship between factor XIII activity and the outcome of gastrointestinal bleedings. Since factor XIII is of great importance in haemostasis and plays a key role in stabilizing the fibrin clot, it can be assumed that a deficiency of factor XIII leads to an unfavorable course of gastrointestinal bleedings. Our hypothesis is that early detection of such a deficiency can prevent a more severe course and that substitution of factor XIII contributes to faster cessation of bleeding, improves patient outcome and reduces the number of red cell concentrates required.
Study Type
OBSERVATIONAL
Enrollment
97
Patients could have had an Factor XIII Injection in clinical routine
Medical University of Graz
Graz, Styria, Austria
Red cell concentrates
Number of red cell concentrates transfused during the hospital stay caused by the gastrointestinal bleeding episode
Time frame: 1 year
Hospitalization
Length of the hospital stay caused by the gastrointestinal bleeding episode
Time frame: 1 year
Interventions
Number of endoscopic, radiological, and surgical interventions for bleeding treatment within the hospital stay caused by the gastrointestinal bleeding episode
Time frame: 1 year
Mortality
In hospital-mortality during the hospital stay caused by the gastrointestinal bleeding episode
Time frame: 1 year
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