The goal of this observational study is to learn about the effect of steroid therapy in patients with COVID-19 ARDS. The main questions it aims to answer are: * Differences between patients with COVID-19 ARDS before and after steroid treatment in BALF single cell landscape, as well as patients with different prognosis. * Differences between COVID-19 and non COVID-19 ARDS patients in BALF single cell landscape. Participants will Choose whether to use or not to utilize steroid treatment based on conditions.
Collect BALF from COVID-19 and non-COVID-19 ARDS patients both before and during remission, then perform single-cell sequencing.
Study Type
OBSERVATIONAL
Enrollment
8
Moderate- or high-dose steroids
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
single-cell analysis in BALF before treatment
collect BALF before and during treatment and perform single-cell sequencing
Time frame: before treatment in ICU
single-cell analysis in BALF after treatment
collect BALF before and during treatment and perform single-cell sequencing
Time frame: After treatment in ICU for 1-4 weeks
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