Exercise-snacks at Work: Impact on Cardiometabolic Parameters

University of Avignon23 enrolled

Overview

The main objective is to measure the effects of intense brief exercise program in the workplace of administrative staff on the cardio-metabolic health

Backgrounds: Very short (\< 1 minute) and intense exercises, entitled "exercise-snacks", have been reported to be effective 1) in improving physical fitness over 6 weeks and 2) in improving vascular function and lowering blood glucose levels over one day. These studies were all carried out in the laboratory. The question therefore arises as to whether these acute vascular and metabolic benefits, as well as those on physical fitness, are sustainable over time following a chronic "exercise-snacks" program applicable in the professional environment to sedentary, overweight people. Aims of this project is therefore to measure the effects of an "exercise-snacks" type physical activity program in the workplace of administrative staff on the cardio-metabolic health and sedentary behaviour of staff.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Sedentary Time Overweight and Obesity Work-Related Condition

Interventions

Exercise-snacks programOTHER

Subjects in the exercise-snacks group will perform 4 "exercise-snacks" sessions per working day for 4 weeks. These sessions will consist of 80 one-to-one walks to be completed as quickly as possible. They will also receive information about their attitudes to physical activity.

Eligibility

Sex: ALLMin age: 30 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * administrative staff, * age between 30 and 60, * body mass index ≥25kg/m², * sedentary time ≥7h/day, * minimum 3 working days on site, * no known cardiovascular or metabolic pathology, social security affiliation or benefit, * ability and willingness to give free, written and informed consent. Exclusion Criteria: * pregnant or breast-feeding women, * anti-hypertensive treatment, beta-blockers and anti-diabetics, * known contraindications to physical activity (articular, cardiac or other), * exercise-induced asthma, * lack of motivation of subjects posing problems of compliance and adherence to the exercise program, * participation in a study in the preceding 3 months, ongoing participation in a clinical trial.

Locations (1)

Avignon University

Avignon, France

Outcomes

Primary Outcomes

Changes in aerobic fitness

Aerobic fitness will be assessed via the Chester step test's prediction of VO2max

Time frame: at inclusion, at the end of the 4-weeks program and 1 month following the end of the program

Secondary Outcomes

Adherence of staff in the experimental group by analyzing accelerometric data.

Total number of exercise-snacks performed during the 4-week program by analysing accelerometers data

Time frame: during the 4-weeks program

Intensity of exercise-snacks

Heart rate during exercise-snacks in % heart rate max

Time frame: during the 4-weeks program

Changes in flow mediated dilation of superficial femoral artery

measured by echocardiography (Vivid Q, GE) , in %

Time frame: at inclusion, at the end of the 4-weeks program

Changes in peak shear rate of superficial femoral artery

measured by echocardiography (Vivid Q, GE) during hyperemia, in s-1

Time frame: at inclusion, at the end of the 4-weeks program

Changes in nitrate mediated dilation of superficial femoral artery

by echocardiography (Vivid Q, GE), in %

Time frame: at inclusion, at the end of the 4-weeks program

Changes in superficial femoral artery compliance

by echocardiography (Vivid Q, GE), in mm2 mmHg-1

Time frame: at inclusion, at the end of the 4-weeks program

Data from ClinicalTrials.gov

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