Enthesis Differences in Rheumatoid Arthritis and Axial Spondyloarthropathy

Istanbul Training and Research Hospital106 enrolled

Overview

The aim of this study is to investigate the sonographic differences in entheses in patients with Rheumatoid arthritis and Axial Spondyloarthropathy.

After recording the demographic data of the patients; 5 enthesis regions 5 enthesis sites were evaluated bilaterally as ''tricipital tendon (TT), quadricipital tendon (QT), proximal patellar tendon (PPT), distal patellar tendon (DPT), achilles tendon (AT)'' will be sonographically evaluated and the presence of hypoechogenicity , tendon thickness increase, power Doppler activity, erosion, presence of entezophyte/calcification will be investigated. The differences between the groups will then be compared.

Study Type

OBSERVATIONAL

Enrollment

106

Conditions

Axial Spondyloarthritis Rheumatoid Arthritis Enthesitis Enthesopathy

Interventions

ULTRASOUNDOTHER

10 enthesis areas will be evaluated in 20 minutes with ultrasound.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Rheumatoid arthritis patients identified according to the 2010 American College of Rheumatology /Europan Leage Against Rheumatism classification criteria, * axial Spondyloarthrtis patients identified according to the Assessment of Spondyloarthritis classification criteria * healthy controls with no history of rheumatic diseases. Exclusion Criteria: * history of limb trauma and surgery in the last 3 months, * metabolic disease (diabetes mellitus, hypothyroidism), * malignant neoplasm, * limitation of range of motion in the extremity, * those who have received corticosteroid injections in the last 3 months, * uncontrollable fibromyalgia.

Locations (1)

Istanbul Training and Resarch Hospital

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Ultrasound enthesis differences between the groups

triceps tendon, quadriceps tendon, proximal patellar tendon, distal patellar tendon and achilles tendons enthesitis scores differences between the groups

Time frame: 2 months

The relationship between ultrasound findings and disease parameters

The relationship between triceps tendon, quadriceps tendon, proximal patellar tendon, distal patellar tendon and achilles tendons enthesitis scores and Clinical disease activity index and BASDAI

Time frame: 2 months

Data from ClinicalTrials.gov

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