PENG Block for Total Hip Arthroplasty

Poznan University of Medical Sciences556 enrolled

Overview

This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the pericapsular nerve group block on postoperative rehabilitation.

The pericapsular nerve group, or PENG block, has been recently described and shows promise in providing analgesia to the hip joint. However, the effect of this block on postoperative rehabilitation is uncertain. This study compares a preoperative PENG block to a placebo before total hip arthroplasty under spinal anesthesia. The primary outcome measure is verticalization, walking distance, ability to go out of bed, active lifting of the limb, range of motion in the hip joint, bending range of motion, and abduction range of motion. The secondary measure is postoperative pain assessment during rehabilitation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

556

Conditions

Hip Osteoarthritis Hip Arthropathy Hip Disease Hip Pain Chronic

Interventions

Ropivacaine 0.5% Injectable SolutionDRUG

20 mL 0.5% ropivacaine will be injected for the PENG block

0,9% normal salineDRUG

20 mL 0.9% normal saline will be injected for the PENG block

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients \> 18 years old undergoing unilateral total hip arthroplasty Exclusion Criteria: * refusal to participate * \< 18 yo * Chronic opioid use * localized infection

Locations (1)

Poznan Univesity of Medical Sciences

Poznan, Wielkopolska, Poland

Outcomes

Primary Outcomes

postoperative Numeric Pain Rating Scale in motion

Numeric Pain Rating Scale. The 11-point numeric scale ranges from '0' representing one pain extreme (e.g. "no pain") to '10' representing the other pain extreme (e.g. "pain as bad as you can imagine" or "worst pain imaginable")

Time frame: Day 2

postoperative Numeric Pain Rating Scale in motion

Time frame: Day 3

postoperative Numeric Pain Rating Scale in motion

Time frame: Day 4

Secondary Outcomes

total opioid consumption

milligrams of intravenous morphine equivalents

Time frame: 96 hours postoperatively

Time to first opioid

Hours to first administration of an intravenous opioid drug

Time frame: 96 hours postoperatively

postoperative Numeric Pain Rating Scale et rest

representing one pain extreme (e.g. "no pain") to '10' representing the other pain extreme (e.g. "pain as bad as you can imagine" or "worst pain imaginable")

Time frame: Day 1

postoperative Numeric Pain Rating Scale et rest

Data from ClinicalTrials.gov

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