Effects of Dexamethasone on Common Bile Duct Cannulation Time

Gujranwala medical college District Headquarters Hospital, Gujranwala80 enrolled

Overview

The main aim of this clinical trial is to evaluate the effects of dexamethasone on common bile duct cannulation time during endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary pathologies. The study will also study the effects of dexamethasone on total procedure time and total fluoroscopy time during ERCP. Participants will be divided into two groups, treatment group and placebo group. Patients in treatment group will receive dexamethasone and those in placebo group will be given normal saline before undergoing ERCP. The results in both groups will be compared to determine the effects of dexamethasone.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Common Bile Duct Diseases Common Bile Duct Calculi Common Bile Duct Stricture Common Bile Duct Neoplasms

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age: 18 years or above * Both genders, male and female patients Exclusion Criteria: * Age younger than 18 years or below * Pregnant females * Pre existing stent in CBD or pancreatic duct * Previous history of ERCP * Patients with billroth II surgery * Anatomical abnormalities * Lack of competence in patients * Roux en Y gastric bypass * Patients with contra indications for steroids like DM

Outcomes

Primary Outcomes

Shortening of CBD cannulation time

To determine the effects of dexamethasone on shortening of CBD cannulation time

Time frame: CBD cannulation time will be calculated from the start of the procedure (0 minutes) till complete CBD cannulation has been achieved through catheter and confirmed by fluoroscopy or procedure abandoned if unsuccessful cannulation by 30 minutes.