Preoperative Nutritional Status and Postoperative Acute Kidney Injury

Rao Sun2,977 enrolled

Overview

There is a high prevalence of postoperative acute kidney injury (AKI) in patients who undergo intra-abdominal surgery, and it is particularly common in the elderly. Identifying high-risk patients for postoperative AKI early can facilitate the development of preventive and therapeutic management strategies. The goal of this retrospective study is to investigate the predictive value of preoperative nutritional status, as measured by three scoring systems - the geriatric nutritional risk index (GNRI), prognostic nutritional index (PNI), and controlling nutritional status (CONUT) score - on postoperative AKI in elderly patients undergoing major abdominal surgery.

Study Type

OBSERVATIONAL

Enrollment

2,977

Conditions

Postoperative Acute Kidney Injury

Interventions

no interventionOTHER

no intervention

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: 1. aged ≥ 65 years 2. intra-abdominal procedures including gastric, colorectal, pancreatic, prostate, and urinary bladder surgeries, as well as abdominal exploration. 3. surgery duration lasting longer than 2 hours. Exclusion Criteria: 1. patients with an American Society of Anesthesiologists (ASA) physical status V. 2. those with concurrent cardiac or renal surgeries. 3. those with end-stage renal disease (i.e. a glomerular filtration rate of 15 mL/min/1.73 m2 or receiving haemodialysis). 4. those did not have sufficient data required for nutritional evaluation or AKI evaluation.

Outcomes

Primary Outcomes

Postoperative acute kidney injury

In accordance with the KDIGO creatinine criteria: a serum creatinine increases of 26.5 mmol/L within 48 hours or 1.5 times baseline within 7 days after surgery.

Time frame: Within 7 days after surgery