Testing the ETM: Examination and Comparison of Different Methods

Early Phase 1CompletedNCT05946031

Virginia Polytechnic Institute and State University87 enrolled

Overview

This study will experimentally assess the comparability of in-lab and remote procedures with hypothetical and real ETM purchase outcomes.

In a between-group within-subject repeated measures design, participants will be randomly assigned to one of two procedures (in-lab or remote; between-group) and complete two conditions (real and hypothetical; within-subject), which include six trials assessing increasing cigarette prices.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Cigarette Smoking

Interventions

Reat ETMDRUG

Exclusive cigarette smokers will be recruited and will be exposed to the real ETM condition in which tobacco purchases are real and they receive products from one randomly selected trial.

Hypothetical ETMDRUG

Exclusive cigarette smokers will be recruited and will be exposed to the hypothetical ETM condition in which tobacco purchases are hypothetical and they don't receive any products.

Eligibility

Sex: ALLMin age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Provide informed consent * Be at least 21 years of age or older * Stable tobacco use patterns for at least three months * Smoke at least 5 cigarettes daily * Use other tobacco products less than weekly * Have access to a computer and internet Exclusion Criteria: * report uncontrolled physical or mental health conditions (e.g., uncontrolled diabetes, high blood pressure, major depressive disorder, etc.), * use of smoking cessation medications (e.g., nicotine replacement, bupropion, varenicline) in the past 30 days, * report concrete, immediate plans to alter/quit using their usual tobacco products in the next 30 days, * be pregnant or lactating

Locations (1)

Fralin Biomedical Research Institute

Roanoke, Virginia, United States

Outcomes

Primary Outcomes

Cigarette demand

Participants will complete purchasing trials in an Experimental Tobacco Marketplace (ETM) with cigarettes increasing in price. Other product prices in the ETM will remain constant. To obtain dependent measures of demand, participants' purchasing of the price-manipulated commodity in the ETM task will be fit to a modified exponential equation to quantify the relationship between the price of each commodity and purchasing: Q=Q0\*10k(exp(-αQ0C)-1) where Q is purchasing of the commodity, C is the price, Q0 is the derived initial purchasing without cost constraints (demand intensity), k is the span of the function in logarithmic units, and α is the demand elasticity.

Time frame: 1 day

Nicotine/tobacco products substitution

Participants will complete purchasing trials in an Experimental Tobacco Marketplace (ETM) with cigarettes increasing in price. Other product prices in the ETM will remain constant. To obtain estimates of substitution of price-constant products in the different ETM conditions, the investigators will use ordinary least squares regression to model the relationship of the price-manipulated product to predict total quantity purchased of the price-constant product.

Time frame: 1 day

Data from ClinicalTrials.gov

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