Non-Pharmacological Nursing Pain Management for Preterm Infants

University of Baghdad105 enrolled

Overview

A randomized controlled trial will be conducted to examine the effect of non-pharmacological nursing pain management strategies in alleviating pain among preterm infants. The study includes a simple random sample of 105 preterm infants with CGA 32- \< 37 weeks were randomly assigned into five groups: routine care (n = 21), breast milk (n = 21), oral sucrose (n = 21), KMC (n = 21), nesting position (n = 21). PIPP-R will be used to subjectively assess the pain intensity after heel stick, and salivary cortisol measures will be used to objectively assess the pain intensity in NICU at Children Welfare Teaching Hospital/ Medical City Complex in Baghdad City.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Enrollment

105

Conditions

Pain Management

Interventions

Eligibility

Sex: ALLMin age: 32 WeeksMax age: 37 WeeksHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Preterm infants whose corrected gestational age from (32 - \<37) weeks of pregnancy, * Preterm infants who do not experience any painful procedure for last 24 hours. * Preterm infants who do not receive any sedation for last 24 hours, and clinically required heel stick. Exclusion Criteria: * Full-term infants whose gestational age (GA) is \>37 weeks * Preterm infants who extremely preterm (\< 28 weeks); very preterm (28-\< 32 weeks) * Preterm infants who are proven or suspected sepsis, major congenital malformations, heart defect, necrotizing enterocolitis (NEC), and neurodevelopmental disability. * Preterm infants who receive respiratory support {Mechanical Ventilation, Continuous Positive Airway Pressure (CPAP), or high-flow support} * Preterm infants who are indicated for surgery * Preterm infants who are contraindicated to oral sucrose * Twins * Preterm infants who had a condition that might influence their physiological and responses to pain, e.g., congenital anomalies or severe illnesses requiring treatment with antiepileptics, muscle relaxants, or analgesic drugs.

Outcomes

Primary Outcomes

Premature Infant Pain Profile - Revised

Premature Infant Pain Profile - Revised measures pain intensity through infant indicators (heart rate, oxygen saturation, brow bulge, eye squeeze). Other indicators in the PIPP-R include gestational age and behavioral state.

Time frame: Two months