Role of MRI in the Evaluation of Hepatic Metastases of Colorectal Cancer

N/ARecruitingNCT05950503

Fondazione Policlinico Universitario Agostino Gemelli IRCCS100 enrolled

Overview

This study wants to evaluate the use of MRI in the managemente of mCRC with liver only metastases.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Colorectal Cancer

Interventions

Hepatic MRIRADIATION

The patients will undergo hepatic MRI in pre-established timepoints

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \> 18 years; * Histological diagnosis of colorectal cancer; * Presence of liver metastases in the staging exams (chest-abdomen CT with contrast medium or PET-CT with 18-FDG); * At least one measurable liver lesion according to RECIST 1.1 criteria; * Adequate organ and marrow function. Exclusion Criteria: * Age \< 18 years; * Inability to undergo MRI; * Major contraindications to liver surgery; * No written informed consent.

Locations (1)

Policlinico Agostino Gemelli

Roma, Italy

RECRUITING

Outcomes

Primary Outcomes

Surgery conversion rates

Negative conversion rate is: patients initially considered operable and subsequently not considered suitable for surgery compared to the total number of patients enrolled. Positive conversion rate is: patients initially deemed ineligible for surgery and subsequently operated, compared to the total number of patients enrolled.

Time frame: 3 years

Secondary Outcomes

Overall survival

Time from enrollment to death

Time frame: 3 years

Central Contacts

Lisa Salvatore, MD, PhD

CONTACT

0630156318 lisa.salvatore@policlinicogemelli.it

Data from ClinicalTrials.gov

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