This study was designed to evaluate the impact of non-pharmacological multimodal interventions including ongoing orientation, sensory correction, setting of familiar circumstance and promotion of sleep enviromnet for prevention of delirium in intensive care unit.
Delirium significantly increases not only the length of the intensive care unit stay and overall mortality, but also the likelihood of persistant cognitive impairment after recovery. However there is no definitive treatment for delirium, thereby it is important to prevent delirium before it occur. Researches also have focused on the prevention of delirium or the reduction of duration of delirium. Several studies evaluated the effect of non-pharmacological treatment, such as improvement of orientation, prevention of sensory deprivation, active pain control and prevention of dehydration, to reduce the occurrence of delirium and the results were inconsistent depending on the patients included. However, there have been no randomized clinical trials that have tested the effect of prevention of delirium by applying non-pharmacological multimodal approaches in the intensive care unit for Korean patients. A randomized controlled trial was planned to evaluate the impact of on-pharmacological multimodal interventions including ongoing orientation, sensory correction, setting of familiar circumstance and promotion of sleep enviromnet for prevention of delirium in intensive care unit in Korea.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
196
Multimodal therapy for prevention of delirium
Seoul National University Hospital
Seoul, South Korea
RECRUITINGNumber of patients with delirium
Delirium assessed by Confusion Assessment Method for the ICU (CAM-ICU)
Time frame: From ICU admission up to day 28 or discharge from ICU or death
Delirium-free days
Delirium assessed by Confusion Assessment Method for the ICU (CAM-ICU)
Time frame: From ICU admission up to day 28 or discharge from ICU or death
Severity of delirium
Confusion Assessment Method for the ICU-7 (CAM-ICU-7) delirium severity score
Time frame: From ICU admission up to day 28 or discharge from ICU or death
Accidental extubation or disconnection of treatment devices
Accidental extubation or disconnection of treatment devices
Time frame: From ICU admission up to day 28 or discharge from ICU or death
ICU and hospital length of stay
Duration of ICU and hospital stay
Time frame: From ICU admission up to day 28 or discharge from ICU or death
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.