At present, there are relatively clear treatment guidelines for colorectal cancer with oligometastases, while the treatment mode for resectable esophageal cancer with oligometastases is not clear and there is a lack of research results in this field. The aim of this study is to provide evidence of the optimal therapy model for the local resectable esophageal cancer with oligometastases ESCC patients, by investigating whether 2-year OS of the patients could benefit from additional local consolidative esophagectomy.
This study was designed as a multicenter, open-label, randomized controlled prospective clinical study. The experimental group (group A) received additional esophagectomy after 3-month systemic treatment, and the control group (group B) received only systemic treatment. 2-year OS, 3-year PFS and OS were observed in the two groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
141
Esophagectomy for esophageal cancer and regional lymph nodes dissection.
Cancer Hospital Chinese Academy of Medical Sciences
Beijing, China
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, China
2-year OS
2-year overall survival
Time frame: Dead time from signing the consent form
3-year OS
3-year overall survival
Time frame: Dead time from signing the consent form
3 years PFS
Recurrence of new metastasis from singing the consent form
Time frame: Recurrence time from signing the consent form
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