The aim of this study is to examine the effect of ethanol (70%) as lock-solution after hemodialysis on: * The frequency of dialysis catheter-related bacteremia among patients under observation of potential complications * Other complications of the use of hemodialysis-catheters eg. dysfunction of the catheter due to thrombosis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
280
Once a week, the catheter will be closed with 3 mL ethanol 70% lock-solution after a completed hemodialysis. The fluid will stay in the catheter until next hemodialysis (ca. 48 hours). The fluid will be aspirated before the hemodialysis. Standard lock-solution of isotonic saline with heparin will be used for the remaining two hemodialysis procedures of the week.
Standard procedure of isotonic saline used as lock-fluid after completed hemodialysis.
Zealand University Hospital
Roskilde, Denmark
Time to hemodialysis catheter-related bacteremia
Time frame: 2 years
Incidence of hemodialysis catheter-related bacteremia
number per year
Time frame: 2 years
Time to exit-site infection
days
Time frame: 2 years
Time to removal of catheter due to infection
days
Time frame: 2 years
Complications eg. catheter-thrombosis and pulmonary embolus
number per year
Time frame: 2 years
Life quality
score of QOL questionaire
Time frame: 2 years
Economical costs
Cost af treatment and cost of complications per patient year compared
Time frame: 2 years
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