Alcohol & Exercise Study

Western University, Canada68 enrolled

Overview

The goal of this clinical trial is to learn if exercise can reduce alcohol craving in heavy social alcohol drinkers. The main questions this project aims to answer are 1) compared to a distraction activity (i.e., coloring), will mild-to-moderate intensity exercise (i.e., walking on a treadmill) reduce alcohol craving; 2) compared to a distraction, will mild-to-moderate intensity exercise reduce the amount of consumption of an alcohol-placebo beverage.

Upon arriving to the study, participants will complete baseline measures assessing for the inclusion and exclusion criteria, as well as baseline alcohol craving and subjective response measures. Participants will then be randomly assigned into the active treatment (exercise) or distraction (coloring) condition. After randomization, participants will consume a low-dose alcohol beverage (BAC=0.03g/dL; equivalent to approximately 1 standard alcohol beverage) within five minutes to induce active alcohol craving. 15 minutes post-beverage consumption, participants will complete the alcohol craving and subjective response measures. At 20 minutes post-beverage consumption, participants will begin their randomly assigned 20-minute activity (exercise or coloring). At approximately 12 minutes into the activity (32 minutes post beverage consumption) and immediately after the activity (44 minutes post beverage consumption), the participants will complete the alcohol craving and subjective response measures. Participants will then be given a tray of three 8oz. cups of water and 3 8oz. cups of an alcohol-placebo beverage and will be allowed to drink as much or as little of the beverages as they would like.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Alcohol-Related Disorders

Interventions

ExerciseBEHAVIORAL

20 minutes of Moderate intensity (40%-59% heartrate reserve) walking on a treadmill.

ColoringBEHAVIORAL

20 minutes of coloring in adult coloring book

Eligibility

Sex: ALLMin age: 19 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Heavy social alcohol drinkers (i.e., alcohol drinkers who consume 10-40 standard alcohol beverages per week and participate in 1-5 binge drinking episodes \[consume 4+/5+ drinks in a sitting for women/men, respectively\]) per week. Exclusion Criteria: * Meets DSM-5 diagnostic criteria for a current moderate or severe alcohol use disorder * Meets DSM-5 diagnostic criteria for a current Moderate or Severe cannabis use disorder * Endorses daily smoking of tobacco * Endorses having a current DSM-5 psychiatric disorder * Endorses having any medical conditions that may interfere with the exercise condition (e.g., knee-replacement, sprained ankle, etc.) * Has a current level of physical activity that exceeds 20 minutes of moderate-to-vigorous physical activity per day * Endorses illicit substance use (i.e., use of illicit substances x\>2 times in the past year) * Has self-reported allergies to pineapple juice, cranberry juice, orange juice, \&/or tonic water * Individuals not proficient in reading, writing, or speaking in English * Women who are trying to conceive or who are pregnant * Women who are currently breastfeeding

Locations (1)

Western University

London, Ontario, Canada

Outcomes

Primary Outcomes

Changes in alcohol craving after alcohol prime dose

It is expected that the exercise condition will lead to larger reductions in alcohol craving (Alcohol Urge Questionnaire) at the mid- and post-intervention time points as compared to the coloring condition.

Time frame: mid-intervention (32 minutes after prime dose consumption) & post-intervention (44 minutes after prime dose consumption)

Post-intervention alcohol beverage consumption

It is expected that individuals in the exercise condition will consume more of the alcohol-placebo beverage (milliliters of beverage consumed) than individuals in the coloring condition.

Time frame: Post-intervention (approximately 50 minutes after prime dose consumption)

Secondary Outcomes

Changes in alcohol wanting after alcohol prime dose

It is expected that the exercise condition will lead to larger reductions in alcohol wanting (Drug Effects Questionnaire: Want More item) at the mid- and post-intervention time points as compared to the coloring condition.

Time frame: mid-intervention (32 minutes after prime dose consumption) & post-intervention (44 minutes after prime dose consumption)

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.