Preoperative CA 19.9 Level Predicts Lymph Node Metastasis in Resectable Adenocarcinoma of the Head of the Pancreas.

Fondazione Policlinico Universitario Campus Bio-Medico2,034 enrolled

Overview

In our multicenter retrospective study, preoperative CA 19.9 levels predicts the presence of lymph node metastasis at final histology in patients underwent pancreatoduodenectomy for pancreatic ductal adenocarcinoma .

A retrospective analysis have been conducted on more than 2.000 patients underwent pancreatoduodenectomy for pancreatic ductal adenocarcinoma radiologically resectable at the preoperative staging. Preoperatory levels of CA 19.9 were measured in order to identify a relation with nodal involvement at the pathological staging.

Study Type

OBSERVATIONAL

Enrollment

2,034

Conditions

Pancreas Cancer

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients undergone pancreatoduodenectomy * No preoperative radiological suspicion of lymph node metastases. Exclusion Criteria: \- Age \< 18

Outcomes

Primary Outcomes

Quantitative data - Preoperatory levels of CA 19.9 (U/ml)

Define relation of quantitative data (CA 19.9 (U/ml)) with nodal positivity at the final pathological report

Time frame: 20 years

Data from ClinicalTrials.gov

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