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Registry of Multicenter Brain-Heart Comorbidity in China

N/ARecruitingNCT05961748
Beijing Tiantan Hospital100,000 enrolled

Overview

This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program. To establish a domestic multi-center, large-scale "brain-heart comorbidity" dynamic database platform including clinical, sample database, image and other multi-dimensional information requirements, through the construction of a multi-center intelligent scientific research integration platform based on artificial intelligence. Any of newly diagnosed cardiovascular related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) \[i.e., ACS\], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels). The data is stored on the brain-heart comorbidity warehouse via a physical server at the institution's data centre or a virtual hosted appliance. The brain-heart comorbidity platform comprises of a series of these appliances connected into a multicenter network. This network can broadcast queries to each appliance. Results are subsequently collected and aggregated. Once the data is sent to the network, it is mapped to a standard and controlled set of clinical terminologies and undergoes a data quality assessment including 'data cleaning' that rejects records which do not meet the brain-heart comorbidity quality standards. The brain-heart comorbidity warehouse performs internal and extensive data quality assessment with every refresh based on conformance, completeness, and plausibility (http://10.100.101.65:30080/login).

Study Type

OBSERVATIONAL

Enrollment

100,000

Conditions

Ischemic Heart DiseaseCardiac ArrestAtrial FibrillationHeart FailureAortic DiseasesSubarachnoid HemorrhageIntracerebral HemorrhageCerebral InfarctionOcclusion and Stenosis of Precerebral ArteriesOcclusion and Stenosis of Cerebellar ArteriesCerebral AneurysmMoyamoya DiseaseArteriovenous Malformation of Cerebral Vessels

Interventions

Multi-disciplinary assessmentOTHER

Multi-disciplinary assessment

Eligibility

Sex: ALLMin age: 18 Years
Medical Language ↔ Plain English
Inclusion Criteria: * age \> 18 years old * Any of newly diagnosed cardiovascular-related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) \[i.e., ACS\], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels). Exclusion Criteria: ·refuse to participate in the registry

Locations (14)

Beijing Tiantan Hospital, Capital Medical University

Beijing, Beijing Municipality, China

RECRUITING

Beijing Anzhen Hospital, Capital Medical University

Beijing, Beijing Municipality, China

NOT_YET_RECRUITING

Beijing Chaoyang Hospital, Capital Medical University

Beijing, Beijing Municipality, China

NOT_YET_RECRUITING

Chinese People's Liberation Army (PLA) General Hospital

Beijing, Beijing Municipality, China

NOT_YET_RECRUITING

Peking University First Hospital

Beijing, Beijing Municipality, China

NOT_YET_RECRUITING

Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, China

NOT_YET_RECRUITING

The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

NOT_YET_RECRUITING

The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China

NOT_YET_RECRUITING

Shenzhen Qianhai Shekou Free Trade Zone Hospital

Shenzhen, Guangdong, China

NOT_YET_RECRUITING

The First Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China

NOT_YET_RECRUITING

...and 4 more locations

Outcomes

Primary Outcomes

Rate of Participants with Composite of All-Cause Mortality and Cardiovascular Outcomes

The occurrence of all-cause mortality, coronary artery disease event, stroke (ischemic or hemorrhagic), heart failure, or atrial fibrillation etc.

Time frame: At discharge/30 days

All-Cause Mortality

The occurrence of death

Time frame: At discharge/30 days

Rate of Participants with Composite of Cardiovascular Outcomes

The occurrence of coronary artery disease event, stroke (ischemic or hemorrhagic), heart failure, or atrial fibrillation etc.

Time frame: At discharge/30 days

Central Contacts

Xiaolin Chen, MD

CONTACT

13810624845cxl_bjtth@163.com

Fa Lin, MD

CONTACT

1368110724013681107240@163.com
Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.