Pilot Study of CBT With tDCS for Adults Being Treated for Obsessive Compulsive Disorder

Rogers Behavioral Health

Overview

This pilot study aims to compare the effect of transcranial direct current stimulation (tDCS) versus sham stimulation, delivered immediately prior to cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD), on patient-reported outcomes. The investigator hypothesize that patients who receive active stimulation will experience greater improvement in OCD symptoms than those who receive sham stimulation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Conditions

Obsessive-Compulsive Disorder

Interventions

transcranial direct current stimulationDEVICE

Current will increase to 1.5 milliamps within 30 seconds and then maintain for 20 minutes

Sham transcranial direct current stimulationDEVICE

Current will increase up to 1.5 milliamps within 30 seconds and then decrease back down over the next 30 seconds to 0 milliamps; subjects will received 0 milliamps for 20 minutes

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Primary diagnosis of Obsessive-Compulsive Disorder (OCD) * Resident of state of Wisconsin * Enrolled in OCD Intensive Outpatient Program (IOP) at Rogers Behavioral Health in Oconomowoc, WI * Ability to communicate effectively using written and spoken English Exclusion Criteria: * Metal in the body of any kind (e.g., braces, pacemakers, metal plates or screws, intracranial electrodes, implanted devices/defibrillators, prostheses) * Currently taking medication that reduces seizure threshold (e.g., clomipramine) * Cranial pathologies (e.g., holes, plates) * History of seizure or black-out concussion * Pregnancy * Previous treatment at Rogers Behavioral Health

Locations (1)

Rogers Behavioral Health

Oconomowoc, Wisconsin, United States

Outcomes

Primary Outcomes

Change in Yale-Brown Obsessive-Compulsive Scale - Self-Report from admission to discharge

Time frame: Up to 12 weeks

Change in Quick Inventory of Depressive Symptomology from admission to discharge

Time frame: Up to 12 weeks

Secondary Outcomes

Number of treatment days between admission and discharge

Time frame: Up to 12 weeks

Change in Obsessive-Compulsive Inventory-Revised from admission to discharge

Time frame: Up to 12 weeks

Change in Quality of life enjoyment and satisfaction questionnaire - short form from admission to discharge

Time frame: Up to 12 weeks

Change in Intolerance of uncertainty scale from admission to discharge

Time frame: Up to 12 weeks

Change in Subjective units of distress from admission to discharge

Time frame: Up to 12 weeks

Data from ClinicalTrials.gov

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