The goal of this observational study is to explore the influence of Covid-19 infection and risk factors of severe outcomes in vulnerable population including patients with chronic liver disease, malignant tumor, autoimmune disease, medical staff. The main questions it aims to answer are: 1. The clinical characteristics of vulnerable population after Covid-19 infection. 2. Risk factors for severe illness in vulnerable groups after infection with the Covid-19. 3. The impact of Covid-19 infection on the progression of underlying diseases. Information of participants will be collected such as gender, age, underlying diseases, medication status, vaccination status, clinical and biochemical indicators. Researchers will compare the mild and severe outcomes after Covid-19 infection to identify the "truly vulnerable" population and explore the potential mechanism and intervention for these population.
Study Type
OBSERVATIONAL
Enrollment
480
Nowadays Covid-19 virus has become milder than before however severe outcomes still happen in people with underlying diseases after infection. For example, previous research indicated cirrhosis was an independent predictor for COVID-19 mortality. More efforts shoud be make to explore the association between underlying diseases and severe COVID-19.
All-cause mortality in patients with underline disease after Covid-19 infection.
All-cause mortality is a measure of the total number of deaths from any cause.
Time frame: 30 days
Severe disease in patients with underline disease after Covid-19 infection.
Severe disease include severe Covid-19 and/or progression of underlying disease.
Time frame: 48weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.