PET-CT Predicting Lymph Nodes Metastasis

N/AActive Not RecruitingNCT05970913

Fudan University280 enrolled

Overview

This study is a single-center prospective clinical study that aims to evaluate the predictive value of preoperative 18F-FDG-PET-CT and 18F-FAPI-PET/CT for lymph node metastasis in patients with non-small cell lung cancer. The final pathological results were used to assess the predictive value of PET-CT for lymph node metastasis.

Study Type

OBSERVATIONAL

Enrollment

280

Conditions

Non Small Cell Lung Cancer Lymph Node Metastasis Positron Emission Tomography

Eligibility

Sex: ALLMin age: 20 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Solitary tumor, or multiple tumors with only ground-glass nodules (GGNs) apart from the primary lesion. * Diameter of the primary lesion ≤5cm, with a CTR between 0.5 and 1. * Pathological confirmation of non-small cell lung cancer (NSCLC) either before or during surgery. * No prior radiotherapy or chemotherapy for initial treatment. * No history of malignant tumors. Exclusion Criteria: * Locally advanced or distant metastasis. * Pleural dissemination observed during surgery. * History of malignant tumors. * Received neoadjuvant therapy. * Histopathological examination reveals lung malignancies other than non-small cell lung cancer (NSCLC).

Locations (1)

Shanghai Cancer Center

Shanghai, China

Outcomes

Primary Outcomes

Predictive value of 18F-FDG-PET/CT and 18F-FAPI-PET/CT for lymph node metastasis

Time frame: from enrollment to 1 month after surgery

Data from ClinicalTrials.gov

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