The Molecular Basis of Inherited Reproductive Disorders

Participants must belong to one of the following categories: * Failure to go through a normal, age-appropriate, spontaneous puberty and low sex steroid levels in the setting of low/normal gonadotropins or, * Abnormally early development of puberty or, * Normal puberty with subsequent development of low gonadotropin levels or, * Evidence of a reproductive disorder with high gonadotropin levels or, * Pre-pubertal individuals with features suggestive of hypogonadotropic hypogonadism or, * Affected and unaffected family members of individuals that fit criteria above