End-stage renal disease (ESRD) is a rare disease in children. Renal transplantation (RT) is the treatment of choice for ESRD in the pediatric population. In France, around 100 pediatric kidney transplants are performed each year. The aim was to evaluate the surgical management of TR and the long-term results.
End-stage renal disease (ESRD) is a rare pathology in children, whose gold standard treatment is a kidney transplant. In France, around 100 pediatric kidney transplants are performed every year. Although the first adult kidney transplants were performed in 1954, pediatric renal transplantation was considered unsafe compared with dialysis, which was preferred. In the 1980s, improved graft selection, optimized pre-transplant management and a better understanding of the immune system led to the development of pediatric kidney transplantation. Despite considerable progress, graft survival in these long-lived patients remains a major challenge. The aim of this study is to evaluate surgical practices in the four French pediatric transplant centers, and to define risk factors for surgical complications.
Study Type
OBSERVATIONAL
Enrollment
500
l'hôpital mère-enfant de Lyon
Bron, France
RECRUITINGl'hôpital mère enfant de Nantes
Nantes, France
RECRUITINGl'hôpital Robert Debré
Paris, France
RECRUITINGSurgical outcomes
To assess surgical outcome in pediatric renal transplantation in terms of * per operative complications (ClassIntra classification) * post operative complications (Clavien Dindo) early \< 30 days and late \> 30 days
Time frame: 10 years
Surgical complications
Evaluate the surgical morbidity of renal transplantation
Time frame: 10 years
Graft Survival
Evaluate graft survival at 1, 5 and 10 years post transplantation
Time frame: 10 years
Return to dialysis
Evaluation of the need to return to dialysis after transplantation : causes and reasons
Time frame: 10 years
Retransplantation
Evaluation the number of patient undegoing another transplantation
Time frame: 10 years
Death
Evaluation of the morbidity of this population
Time frame: 10 years
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l'hôpital Necker Enfants malades.
Paris, France
RECRUITING